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  • 产品名称:Testosterone 17-Beta-Dehydrogenase 3 (HSD17B3), ELISA Kit

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简单介绍:
Testosterone 17-Beta-Dehydrogenase 3 (HSD17B3), ELISA Kit
详情介绍:
Product Name

Testosterone 17-Beta-Dehydrogenase 3 (HSD17B3), ELISA Kit

Full Product Name

Porcine Testosterone 17-Beta-Dehydrogenase 3 (HSD17B3) ELISA Kit

Product Gene Name

HSD17B3 elisa kit

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Request for Current Manual Insert
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OMIM
264300
Species Reactivity
Porcine
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit *****s are dynamic research tools and sometimes they may be updated and improved. If the format of this ***** is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the *****. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of HSD17B3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for HSD17B3 purchase
MBS9368083 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent *****) Kit for analyzing the presence of the Testosterone 17-Beta-Dehydrogenase 3 (HSD17B3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HSD17B3. The ELISA analytical biochemical technique of the MBS9368083 kit is based on HSD17B3 antibody-HSD17B3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HSD17B3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HSD17B3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control *****s assessing reproducibility identified the intra-***** CV (%) and inter-***** CV(%).
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NCBI/Uniprot data below describe general gene information for HSD17B3. It may not necessarily be applicable to this product.
NCBI GI #
4557649
NCBI GeneID
3293
NCBI Accession #
NP_000188.1 [Other Products]
NCBI GenBank Nucleotide #
NM_000197.1 [Other Products]
UniProt Secondary Accession #
Q5U0Q6[Other Products]
UniProt Related Accession #
P37058[Other Products]
Molecular Weight
29,109 Da
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NCBI Official Full Name
testosterone 17-beta-dehydrogenase 3
NCBI Official Synonym Full Names
hydroxysteroid (17-beta) dehydrogenase 3
NCBI Official Symbol
HSD17B3  [Similar Products]
NCBI Official Synonym Symbols
EDH17B3; SDR12C2
  [Similar Products]
NCBI Protein Information
testosterone 17-beta-dehydrogenase 3
UniProt Protein Name
Testosterone 17-beta-dehydrogenase 3
UniProt Synonym Protein Names
17-beta-hydroxysteroid dehydrogenase type 3; 17-beta-HSD 3; Short chain dehydrogenase/reductase family 12C member 2; Testicular 17-beta-hydroxysteroid dehydrogenase
Protein Family
Testosterone 17-beta-dehydrogenase
UniProt Gene Name
HSD17B3  [Similar Products]
UniProt Synonym Gene Names
EDH17B3; SDR12C2; 17-beta-HSD 3  [Similar Products]
UniProt Entry Name
DHB3_HUMAN
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NCBI Summary for HSD17B3
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008]
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UniProt Comments for HSD17B3
HSD17B3: Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH. Defects in HSD17B3 are the cause of male pseudohermaphrodism with gynecomastia (MPH). These individuals have unambiguous female external genitalia at birth, but fail to menstruate at the time of expected puberty and instead virilize as evidenced by growth of the phallus. Breast development may or may not take place. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.

Protein type: Lipid Metabolism - androgen and estrogen; EC 1.1.1.64; Oxidoreductase

Chromosomal Location of Human Ortholog: 9q22

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle

Molecular Function: testosterone 17-beta-dehydrogenase (NADP+) activity

Biological Process: androgen biosynthetic process; male genitalia development; steroid metabolic process

Disease: 17-beta Hydroxysteroid Dehydrogenase Iii Deficiency
Research Articles on HSD17B3
1. Expression of the genes HSD3B1, HSD17B3, and SRD5A2 was significantly increased in BPH tissues compared to normal adjacent prostate tissues.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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