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  • 产品名称:14-3-3, Monoclonal Antibody

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简单介绍:
14-3-3, Monoclonal Antibody
详情介绍:
Product Name

14-3-3, Monoclonal Antibody

Full Product Name

14-3-3 monoclonal Antibody

Product Synonym Names
14 3 3 antibody; 14 3 3 protein beta antibody; 14 3 3 protein beta/alpha antibody; 14 3 3 protein zeta antibody; 14 3 3 zeta antibody; 14-3-3 protein beta/alpha antibody; 14-3-3 protein/cytosolic phospholipase A2 antibody; GW128 antibody; HS1 antibody; KCIP 1 antibody; MGC111427 antibody; MGC126532 antibody; MGC138156 antibody; Protein 1054 antibody; Protein kinase C inhibitor protein 1 antibody; Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein delta polypeptide antibody; Tyrosine 3/tryptophan 5-monooxygenase activation protein; zeta polypeptide antibody; YWHAB antibody; YWHAD antibody; YWHAZ antibody; YWHAZ antibody
Product Gene Name

anti-14-3-3 antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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3D Structure
ModBase 3D Structure for P29310
Clonality
Monoclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human, Mouse, Rat, Pig, Monkey, Rabbit, Dog, Sheep, Bovine
Purity/Purification
Affinity Purified
Form/Format
Colorless liquid
100 ug (0.5 mg/ml) immunoaffinity purified mouse monoclonal antibody in PBS containing 1 mg/ml BSA and 1.5 mM sodium azide and 50% glycerol.
Concentration
0.5 mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C for 12 months.
The antibody solution should be gently mixed before use.
Other Notes
Small volumes of anti-14-3-3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-14-3-3 antibody
The 14-3-3 proteins comprise a family of highly conserved acidic proteins which play a role in both signal transduction and the cell cycle by binding to and regulating several different proteins. The family of proteins is present in particularly high concentrations in mammalian brain and may be involved in the regulation of neuronal activity. The 14-3-3 proteins exist as either homo- or heterodimers which interact via their N-terminal domains and are subject to phosphorylation by protein kinase C.
Product Categories/Family for anti-14-3-3 antibody
14-3-3
Applications Tested/Suitable for anti-14-3-3 antibody
Western Blot (WB)
Application Notes for anti-14-3-3 antibody
Western Blot: 1-4 ug
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NCBI/Uniprot data below describe general gene information for 14-3-3. It may not necessarily be applicable to this product.
NCBI GI #
62471695
NCBI GeneID
36059
NCBI Accession #
NP_001014515.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001014515.2 [Other Products]
UniProt Primary Accession #
P29310 [Other Products]
UniProt Secondary Accession #
O01665; Q0E9D5; Q0E9D6; Q0E9D7; Q8IGB9; Q8MKV5; Q9V5G6; A4UZB2; A4UZB3; C1C593; C9QP27[Other Products]
UniProt Related Accession #
P29310[Other Products]
Molecular Weight
28,304 Da
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NCBI Official Full Name
14-3-3zeta, isoform J
NCBI Official Symbol
14-3-3zeta  [Similar Products]
NCBI Official Synonym Symbols
14-3-3; 14-3-3 zeta; 14-3-3-Leo; 14-3-3-zeta; 14-3-3leo; 14-3-3ZETA; 2G1; 4-3-3 zeta; 5.11; 549; BEST:GH05075; CG17870; D14-3-3; d14-3-3zeta; D14-3-3zeta; DmelCG17870; K; l(2)07103; l(2)46CFe; l(2)46Ee; leo; Leo; LEO; par-5; Par-5; PAR-5; PAR5
  [Similar Products]
NCBI Protein Information
CG17870 gene product from transcript CG17870-RE
UniProt Protein Name
14-3-3 protein zeta
UniProt Synonym Protein Names
14-3-3-like protein; Protein Leonardo
Protein Family
14-3-3 protein
UniProt Gene Name
14-3-3zeta  [Similar Products]
UniProt Synonym Gene Names
14-3-3; 14-3-3EZ; leo; THAP  [Similar Products]
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UniProt Comments for 14-3-3
Required in Raf-dependent cell proliferation and photoreceptor differentiation during eye development (PubMed:9159395). Acts upstream of Raf and downstream of Ras, and is essential for viability (PubMed:9159395). Acts as a negative regulator of the slo calcium channel via its interaction with slo-binding protein slob (PubMed:10230800). Inhibits yki activity by restricting its nuclear localization (PubMed:19900439). Binds to and promotes the activity of phosphoinositide 3-kinase Pi3K68D which converts phosphatidylinositol to phosphatidylinositol-3-phosphate and promotes maturation of early endosomes (PubMed:27015288).
Research Articles on 14-3-3
1. The Khc73 stalk/14-3-3/NudE pathway defines a physical connection that coordinates the activities of multiple motor proteins to precisely position the spindle.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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